Which of the following is TRUE regarding the treatment of infantile esotropia?

The assertion that treatment of infantile esotropia may require surgery or botulinum toxin is accurate because this condition, characterized by an inward turning of the eye, often necessitates intervention to improve ocular alignment and visual function. Surgical options are frequently employed to realign the eyes, particularly when the esotropia is significant and persistent, as is commonly the case with infantile esotropia.

In some instances, botulinum toxin can be used as a non-surgical alternative, providing a temporary means of treating the condition, particularly in patients who may not be ideal candidates for surgery or when immediate surgical intervention is not preferable. The use of either surgery or botulinum toxin is crucial in treating this condition to reduce the risk of vision problems, such as amblyopia or suppressed binocular vision.

The other choices do not hold true in the context of this question. Surgical options are indeed available, and while treatment can lead to favorable outcomes, it is not guaranteed to be successful in every case. Additionally, infantile esotropia is usually identified in early infancy, not exclusively at birth, allowing for earlier intervention.